The TBC1D3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TBC1D3C, and TBC1D3G. This antibody recognizes Human antigen. The TBC1D3 Antibody has been validated for the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Function: Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.
Post-translational Modifications: Ubiquitinated by a CUL7-based E3 ligase, which leads to proteasomal degradation. Palmitoylation is required for membrane localization and protects TBC1D3 from ubiquitination